About Course
This course introduces the fundamentals and basics of bioinformatics, molecular biology concepts related to computer applications, common databases and resources, sequence analysis, alignments, BLAST, disease-related databases, motif discovery, Linux, and reproducibility in bioinformatics.
Course abbreviation: IND-BIO
Instructor: Dr. Radwa Sharaf / Dr. Mohamed Hamed
Workload: 12 lectures, 3 hours each. Total workload: 48 hours: 36 hours of lectures and tutorials and 6 hours of self studies.
Entrance requirements: Basic knowledge of biology and computer science.
Used media: PowerPoint presentation
Objectives
- Understand the fundamentals and basics of bioinformatics
- Gain knowledge about mathematics of bioinformatics
- Understand the relationship between molecular biology and computer applications
- Learn common bioinformatics databases and resources
Competences to be Developed
- Analyze DNA and protein sequences to obtain similarity scores
- Apply pairwise and multiple sequence alignments using BLAST
- Develop research projects and interpret results
- Become familiar with different bioinformatics databases and resources
Assessment
- Assignments (40%)
- Final Exam (60%)
- Project
Course Content
Week 1: Introduction to Bioinformatics
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Introduction to Bioinformatics
00:00
Week 2: Introduction to Next-generation Sequencing
Week 3: Sequence File Formats
Week 4: Sequence Variations
Week 5: Alignments
Week 6: BLAST Algorithm
Week 7: Bioinformatics Databases and Resources
Week 8: Disease-related Databases I
Week 9: Disease-related Databases II
Week 10: Disease-related Databases III
Week 11: Motif Discovery
Week 12: Linux for Bioinformatics I
Week 13: Linux for Bioinformatics II
Week 14: Linux for Bioinformatics III
Week 15: Data Reproducibility in Bioinformatics
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